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In older men the risk of a broken bone is written in the ebb and flow of certain sex hormones, according to a study published in the Journal of Clinical Endocrinology & Metabolism in September. Under scrutiny are the hormones estradiol and testosterone, along with a substance known as sex hormone binding globulin, all three of which, when present in abnormal levels, can lead to a threefold increase in the risk of breaking a bone. Based on the evidence, the study’s co-author from Oregon Health and Science University called for a revision of the procedures behind the assessment of fracture risk in this population.
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